GWAS-related eQTLs across different cancer types
We identified 337,131 eQTLs that overlap with GWAS linkage disequilibrium (LD) regions (r² ≥ 0.5).
|
Cancer type
|
eQTL type
|
tagSNP
|
Gene position (hg19)
|
p-value
|
|||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| THYM | cis | rs10857712 | 1 | rs10857712 | chr10:135225666 | MTG1 | chr10:135207621-135234173:+ | 0.32 | 5.4 | 4.87E-7 | Systemic lupus erythematosus |
| THYM | cis | rs9815354 | 1 | rs10865914 | chr3:41919499 | ULK4 | chr3:41288091-42003660:- | -1 | -11.02 | 1.12E-18 | Diastolic blood pressure |
| THYM | cis | rs703842 | 1 | rs10877012 | chr12:58162085 | FAM119B | chr12:58166383-58176323:+ | 0.42 | 5.62 | 1.9E-7 | Multiple sclerosis |
| THYM | cis | rs703842 | 1 | rs10877012 | chr12:58162085 | TSFM | chr12:58176536-58191367:+ | -0.27 | -4.75 | 7.08E-6 | Multiple sclerosis |
| THYM | cis | rs703842 | 1 | rs10877013 | chr12:58165085 | FAM119B | chr12:58166383-58176323:+ | 0.42 | 5.82 | 8.05E-8 | Multiple sclerosis |
| THYM | cis | rs703842 | 1 | rs10877013 | chr12:58165085 | TSFM | chr12:58176536-58191367:+ | -0.28 | -5.1 | 1.74E-6 | Multiple sclerosis |
| THYM | cis | rs703842 | 1 | rs10877014 | chr12:58167661 | FAM119B | chr12:58166383-58176323:+ | 0.41 | 5.83 | 7.7E-8 | Multiple sclerosis |
| THYM | cis | rs703842 | 1 | rs10877014 | chr12:58167661 | TSFM | chr12:58176536-58191367:+ | -0.28 | -5.16 | 1.33E-6 | Multiple sclerosis |
| THYM | cis | rs703842 | 1 | rs10877015 | chr12:58167788 | FAM119B | chr12:58166383-58176323:+ | 0.42 | 5.72 | 1.22E-7 | Multiple sclerosis |
| THYM | cis | rs703842 | 1 | rs10877015 | chr12:58167788 | TSFM | chr12:58176536-58191367:+ | -0.29 | -5.12 | 1.6E-6 | Multiple sclerosis |
| THYM | cis | rs703842 | 1 | rs10877019 | chr12:58172929 | FAM119B | chr12:58166383-58176323:+ | -0.42 | -5.72 | 1.22E-7 | Multiple sclerosis |
| THYM | cis | rs703842 | 1 | rs10877019 | chr12:58172929 | TSFM | chr12:58176536-58191367:+ | 0.29 | 5.12 | 1.6E-6 | Multiple sclerosis |
| THYM | cis | rs2275426 | 1 | rs10890352 | chr1:46283628 | CCDC163P | chr1:45960581-45965646:- | -0.49 | -5.85 | 6.8E-8 | Body mass index |
| THYM | cis | rs2275426 | 1 | rs10890354 | chr1:46305347 | CCDC163P | chr1:45960581-45965646:- | -0.49 | -5.85 | 6.8E-8 | Body mass index |
| THYM | cis | rs2275426 | 1 | rs10890361 | chr1:46346234 | CCDC163P | chr1:45960581-45965646:- | -0.49 | -5.85 | 6.8E-8 | Body mass index |